Esme Cullen (born Esme Anne Platt and later Esme Anne Evenson) was born 1895 and lived in Columbus, Ohio where at age 16 was treated by her future husband Dr. Cullen after she broke her leg falling out of a tree. She was forced by her parents to marry a man named Charles Evenson who abused her.
After realizing she was pregnant, Esme left her husband and gave birth to a son. After losing her son to a lung infection, Esme attempted to commit suicide by jumping from a cliff (Edward tells Bella she "fell"). Esme was presumed dead and taken to the morgue... but she was still alive.
Dr. Carlisle Cullen heard her beating heart and remembered her. He didn't want her to die, so he chose to change her into a vampire like himself. Edward was the first human Carlisle had changed and Esme the second. Carlisle and Esme fell in love and were married.
http://images2.wikia.nocookie.net/__cb20120728044553/twilightsaga/images/c/c1/Esme-484606_429620203747878_1896270186_n-1.jpg
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